Smad3 molecular weight
WebbWe measured the expression levels of proteins involved in the wrinkle formation pathway, c-Jun N-terminal kinase (JNK)/c-FOS/c-Jun/MMPs/Smad3 pathway, and mRNA expression levels of elasticity factors—transforming growth factor-β receptor I (TGF-β RI), procollagen type I, and collagen type I—in the dorsal skin of mice exposed to UVB … WebbThis antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human SMAD2. The molecular weight of unphosphorylated forms of Smad2 is 52 kDa …
Smad3 molecular weight
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WebbFind smad3 and related products for scientific research at MilliporeSigma. US EN. Applications Products Services Support. Advanced Search. Structure Search. Search … WebbNCBI Full Gene Name SMAD family member 3 NCBI Gene Aliases JV15-2, MADH3, LDS3, HsT17436, HSPC193, LDS1C Clonality Polyclonal Molecular Weight 48 kDa Biorbyt 5 Orwell Furlong Cowley Road Cambridge, Cambridgeshire CB4 0WY United Kingdom Phone: +44 (0)1223 815 212 +44 (0)1223 280 240 (fax) +44 (0)1223 280 240 Email: [email protected]
Smads are roughly between 400 and 500 amino acids long, and consist of two globular regions at the amino and carboxy termini, connected by a linker region. These globular regions are highly conserved in R-Smads and Co-Smads, and are called Mad homology 1 (MH1) at the N-terminus, and MH2 at the C-terminus. The MH2 domain is also conserved in I-Smads. The MH1 domain is primarily involved in DNA binding, while the MH2 is responsible for the interaction with other Sm… WebbPredicted molecular weight: 48 kDa. Avoid using milk, casein, and phopshorylated proteins in general in the blocking buffer and in the antibody diluent. We recommend a solution of 5% BSA (bovine serum …
Webb1 apr. 2024 · Phospho-SMAD3 (Ser423, Ser425) Polyclonal Antibody Invitrogen catalog: 44-246G total number of products: 41 domestic rabbit polyclonal reactivity: human, mouse modification: phosphorylated application: western blot, immunocytochemistry citations: 5 quantity: 100 µL price: US 482 to the supplier SMAD3 phospho S423/phospho S425 … WebbSMAD3, also named as hMAD 3 or Mad3, is a 425 amino acid protein, which contains one MH1 domain and one MH2 domain. SMAD3 localizes in the nucleus and cytoplasm. SMAD3 plays an essential role in …
WebbConstitutive proteasomal degradation of steady-state Smad3 is regulated by Axin. ( A) HaCaT cells were pretreated with 10 μM SB-431542 for 6 h, and 50 μg/mL CHX or 25 μM MG-132 was then added as indicated. Total cell lysates were probed for endogenous Smad3 and Smad2. γ-Tubulin was used as a loading control.
Webb7 apr. 2024 · To further explore the necessary role of Smad3 in SARS-CoV-2 N-induced AKI, we overexpressed the SARS-CoV-2 N protein in the kidneys of Smad3 KO-db/m, Smad3 WT-db/m, Smad3 KO-db/db, and... data factory doesnt support cherry pickWebbMembers of the SMAD family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the … bitmap set background color c#WebbAnti-phospho-Smad3 (Ser423/425) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Smad3 (Ser423/425) also known as MAD Mothers against DPP homolog 3 & has been validated in WB. Anti-phospho-Smad3 (Ser423/425) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available … data factory dynamics 365Webb21 mars 2024 · Genomic Locations for SMAD3 Gene Latest Assembly chr15:67,063,763-67,195,173 (GRCh38/hg38) Size: 131,411 bases Orientation: Plus strand Previous … bitmap screenshotWebbIP. IF. Confocal immunofluorescent analysis of HT1080 cells, serum-starved (left), or treated with hTGF-β3 #8425 (100 ng/ml, 30 min; right), … data factory duplicate rowsWebb31 mars 2024 · Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. Federal government websites often end in .gov or .mil. datafactory downloadWebbThe molarity calculator equation Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Keywords: SIS3 1009104-85-1 SIS 3 SIS-3 TGF-beta/Smad Transforming growth factor beta Smad3 phosphorylation myofibroblast differentiation fibroblasts TGF-β1 Inhibitor inhibitor inhibit Your Recently Viewed Products: data factory dynamic content concat